Molecular, Cellular, and Developmental Biology at the University of Michigan
Molecular, Cellular, and Developmental Biology
Molecular, Cellular, and Developmental Biology

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Faculty of 1000 Ranks Shu Quan's Article Highest in Microbiology and Related Areas


Shu Quan's article on Spy was ranked by Faculty of 1000 as the 6th most highly ranked article in microbiology for the year 2011 and was one of the top 25 of all articles ranked in all disciplines in 2011 by Faculty of 1000.

Quan's paper, "Genetic selection designed to stabilize proteins uncovers a chaperone called Spy," Nat Struct Mol Biol, 18:262-69, 2011, was also the the paper was the subject of a news and views in Nature. Read the comments from the Faculty of 1000.
Researchers testing the ability of engineered E. coli cells to stabilize unstable proteins in vivo, stumbled upon a new protein chaperone called Spy that suppresses protein aggregation and aids protein refolding. Spy is shaped unlike any other previously studied chaperone and can increase the steady-state levels of a set of unstable protein mutants up to 700-fold.
from F1000 - Top 7 in Microbiology.
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Faculty Members evaluate and rate the most important papers in their field. To see the latest rankings, search the database, and read daily evaluations, visit http://f1000.com.

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