Welcome to the Maddock Lab

The laboratory of Dr. Janine R. Maddock is part of the Department of Molecular, Cellular and Developmental Biology at the University of Michigan.

Our work is aimed at understanding basic developmental questions using approaches in molecular genetics, biochemistry, and cell biology complemented by bioinformatics, genomics and proteomics. Two major areas of ongoing projects in the laboratory are under study:

(1) to understand how the OBG-family of GTP-binding proteins function in Escherichia coli and other bacterial species, and in Saccharomyces cerevisiae, and

(2) to understand how asymmetry is established and maintained in bacteria, particularly in Escherichia coli and Pseudomonas aeruginosa.